Yes, to enroll in any Engineering degree program at the University of Pisa, you are required to take the TOLC-I (Online Test by CISIA for Engineering), which is designed to assess your initial knowledge. You can take the TOLC-I starting from the second-to-last year of your upper secondary school, either in Italy or abroad.
You can find more information about the TOLC here (https://www.cisiaonline.it/tolc/tolc-i/struttura-della-prova-e-sillabo).
